Nemo is a forward-time, individual-based, genetically explicit, and stochastic simulation program designed to study the evolution of life history/phenotypic traits and population genetics in a flexible (meta-)population framework.

Nemo implements many different life cycle events and evolvable traits with a variety of genetic architectures (see below). Species interaction between a parasite and its host can also be modeled (i.e., Cytoplasmic-Incompatibility inducing endosymbiont: Wolbachia). All this is framed within a flexible metapopulation model that allows for patch-specific carrying capacities, dispersal rates, stochastic extinction/harvesting rates, and demographic stochasticity. Populations can be dynamically modified during a simulation, allowing for population bottlenecks, patch fusion/fisson, population expansion, etc. Spatially and temporally heterogenous selection on quantitative traits can also be modelled with similar variation of local phenotypic optima.

Nemo's interface is a simple text file containing the simulation parameters and their values. Each parameter can have several argument values, which allows many simulations to be run from a single parameter file. Parameters can also be set with temporal values that will automatically modify the simulation settings during a run.